Mike Ziegler, M.D.
Professor of Medicine
Phone: (619) 543-2885
Dr. Ziegler's research on sympathetic nervous control of the cardiovascular system bridges basic and clinical research in over 400 publications. His recent studies have examined how adrenergic genetic polymorphisms alter control of blood pressure in man and transgenic mouse. His NASA research has examined why astronauts lose postural control of blood pressure on their return from space flight. He has received a NASA research award and has chaired several NIH Review Committees. He is particularly interested in mechanisms that allow the brain to use the sympathetic nervous system to alter physiology and the consequences of stress and sleep apnea on blood pressure control. He specializes in the clinical care of patients with high blood pressure and postural hypotension.
Ziegler MG, Elayan H, Milic M, Sun P, Gharaibeh M. Epinephrine and the metabolic syndrome. Curr Hypertens Rep. 2012
Ziegler MG, Milic M. New therapies for postural hypotension. Hypertension. 2012 Mar;59(3):548-9
Elayan H, Milic M, Sun P, Gharaibeh M, Ziegler MG. Chronic β2 adrenergic agonist, but not exercise, improves glucose handling in older type 2 diabetic mice. Cell Mol Neurobiol. 2012
Ziegler MG, Milic M, Sun P, Tang CM, Elayan H, Bao X, Cheung WW, O'Connor DT. Endogenous epinephrine protects against obesity induced insulin resistance. Auton Neurosci. 2011
Ziegler MG, Milic M, Sun P. Antihypertensive therapy for patients with obstructive sleep apnea. Curr Opin Nephrol Hypertens. 2011
Ziegler MG, Milic M, Elayan H. Cardiovascular Regulation in Obstructive Sleep Apnea. Drug Discov Today Dis Models. 2011
Shi SJ, Platts SH, Ziegler MG, Meck JV. Effects of promethazine and midodrine on orthostatic tolerance. Aviat Space Environ Med. 2011